Lanthanum carbonate is not associated with QT interval modification in hemodialysis patients
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چکیده
منابع مشابه
Lanthanum carbonate is not associated with QT interval modification in hemodialysis patients
UNLABELLED Lanthanum carbonate is an efficacious noncalcium, nonresin phosphate-binder that is being increasingly used in chronic kidney disease stage 5 (CKD-5) dialysis patients. Available evidence has indicated that QT interval changes correlate with mortality in healthy subjects and in dialysis patients. Experimental studies have suggested the possibility that lanthanum carbonate may produce...
متن کاملChanges in QT interval before and after hemodialysis
Background: Cardiovascular mortality and morbidity are high in chronic renal failure (CRF) patients. Increased dispersion of QT intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. This study was conducted to assess the effect of hemodialysis (HD) on corrected QT (QTc) intervals and their dispersions (QTd) in chronic hemodialyzed patients. Methods: Fifty-eight p...
متن کاملEffects of cinacalcet treatment on QT interval in hemodialysis patients
OBJECTIVE Cinacalcet is a calcimimetic drug that acts via calcium-sensing receptors (CaSRs) and increases the sensitivity of CaSRs on the parathyroid gland; thus, it lowers calcium and phosphorus levels as well as parathormone levels. Prolongation of the QT interval is recognized as a risk factor for the development of ventricular arrhythmias and sudden death. Patients with end-stage renal dise...
متن کاملSurvival advantage of lanthanum carbonate for hemodialysis patients with uncontrolled hyperphosphatemia.
BACKGROUND Lanthanum carbonate is a non-calcium phosphate binder that is effective for the treatment of hyperphosphatemia. However, it is unknown whether treatment with lanthanum affects survival. METHODS We retrospectively collected data on maintenance hemodialysis patients at 22 facilities (n = 2292) beginning in December 2008, a time point immediately prior to the commercial availability o...
متن کاملQT Interval and QT Dispersion in Patients Undergoing Hemodialysis: Revisiting the Old Theory
AIMS We sought to explore the response of the corrected QT (QTc) interval duration and QT dispersion (QTD) to hemodialysis. METHODS We enrolled 50 patients with end-stage renal disease undergoing regular hemodialysis. Blood samples were drawn for measurement of serum electrolytes, and a 12-lead ECG was performed to measure the QTc interval duration and QTD, immediately before and just after d...
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ژورنال
عنوان ژورنال: Clinical Pharmacology: Advances and Applications
سال: 2010
ISSN: 1179-1438
DOI: 10.2147/cpaa.s10218